STEM CELL TECHNOLOGIES AND THERAPY

“It may be that, some ages hence... the restoration of grey hairs to juvenility and the renewing of the exhausted marrow may at length be elicited without a miracle”

Joseph Glanvill,
1661AD

Stem Cells

Axordia's patent portfolio originated from work carried out at the University of Sheffield in the laboratories of Prof. Peter Andrews and Prof. Harry Moore. The portfolio covers several methods important in the differentiation of stem cells and also gives broad-ranging coverage of Cytotrophoblast stem cells and their applications.

WO/2002/016620 Modulation of stem cell differentiation The manipulation of human embryonic stem cells (HESCs) by RNAi directed to Notch/Wnt mRNA including methods to manipulate HESCs, RNAi constructs and vectors for the production of siRNA.
WO/2002/077204 Stem cell differentiation. The use of Notch/Wnt ligands (polypeptides) in the modulation of hES cell differentiation.
WO/2003/068961 Method to modify differentiation of pluripotental stem cells Additional Notch/Wnt targets in particular Hes/HERP transcription factors.
WO/2006/111706 Cytotrophoblast stem cell The isolation of human cytrophoblast stem cells including methods to derive cytrophoblast stem cells, endovascular cells derived from the cytrophoblast stem cells, uses of the cytrophoblast stem cells to modulate the immune system and hybrids of cytrophoblast stem cells and differentiated cells.

Axordia has other patent applications in related areas of stem cell research that have not yet published.